Oyasumi Punpun. A story of a certain guy's life and it starts off when he's young like First grade or somethin' and progresses. 110 Chapters in, he is now 20 years old. Basically fell in love and never really fell out and the person keeps coming in and out of his life.
Yeah...depression and life happens and shit, I'm really hooked. Inio Asano's manga's are not goofy(not really) or anything but just have the sad, happy, funny, and angry parts of life. Every release of his has actually made me feel. I acutally get a bit depressed after reading a voume of this specific manga.